Absolutely, staying compliant with sales tax is crucial for e-commerce businesses, especially as they grow. First, it’s essential to understand the sales tax laws in each state where you have a tax obligation. Utilize automated tax software to streamline calculations and filings. Regularly update your systems to accommodate changes in legislation. Furthermore, consider leveraging sales tax registration services to simplify the process of registering in different states, ensuring that you meet all regulatory requirements efficiently. Being proactive about compliance not only mitigates risk but also builds customer trust in your business.